abstract：:The umbilical cord (UC) is a vital connection between fetus and placenta. It constitutes a stable connection to the fetomaternal interface, while allowing the fetal mobility that is of great importance for fetal development in general and fetal neuromotor development in particular. This combination of mechanical stabi...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Bosselmann S,Mielke G

更新日期：2015-08-01 00:00:00

abstract：:Introduction: Use of hormone therapy (HT) has declined dramatically in recent years. Some studies have reported that HT use before a diagnosis of breast cancer (BC) may be a prognostic factor in postmenopausal patients. This study aimed to examine the prognostic relevance of HT use before BC diagnosis. Methods: Four B...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Rauh C,Schuetz F,Rack B,Stickeler E,Klar M,Orlowska-Volk M,Windfuhr-Blum M,Heil J,Rom J,Sohn C,Andergassen U,Jueckstock J,Fehm T,Loehberg CR,Hein A,Schulz-Wendtland R,Hartmann A,Beckmann MW,Janni W,Fasching PA,Häb

更新日期：2015-06-01 00:00:00

abstract：:Aim: Endometriosis is a chronic gynaecological disorder with manifold symptoms and psychosocial effects on the lives of affected women. The prevalence of endometriosis is estimated to be up to ten percent of women of reproductive age. As a result of its unclear aetiology, only limited treatment options are available. ...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Kundu S,Wildgrube J,Schippert C,Hillemanns P,Brandes I

更新日期：2015-05-01 00:00:00

abstract：:The term "deciduosis" is used to describe the severe pregnancy-associated occurrence of ectopic decidua with a usually asymptomatic course. We report on two cases of massive maternal intra-abdominal bleeding due to such symptomatic changes. The complications arose at different time points for the two cases: prepartum ...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Lüdders DW,Henke RP,Saba M,Raddatz L,Soliman A,Malik E

更新日期：2015-03-01 00:00:00

abstract：:The therapy for patients with breast cancer has developed markedly in the past ten years. Our understanding of the molecular biology of tumours and the characteristics of the patients has shaped the recent advances. In this review we present the latest knowledge about the therapy for breast cancer. There are new tests...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Maass N,Schütz F,Fasching PA,Fehm T,Janni W,Kümmel S,Kolberg HC,Lüftner D,Wallwiener M,Lux MP

更新日期：2015-02-01 00:00:00

abstract：:Introduction: Defects of the levator ani muscle complex could represent a pathophysiological link between vaginal birth trauma and urogynecological symptoms many years later. The aim of our study was to determine the prevalence of levator ani muscle defects using 3D or 4D ultrasound and palpation in urogynecological p...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Albrich S,Rommens K,Steetskamp J,Weyer V,Hoffmann G,Skala C,Zahn E

更新日期：2015-01-01 00:00:00

abstract：:The current law on the protection of expectant and nursing mothers largely rules out surgical activities during pregnancy for female doctors who perform surgical roles in hospitals. The proportion of female junior staff in gynaecology amounts to 80 %, and, for many of these women, surgical further training is not poss...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Knieper C,Ramsauer B,Hancke K,Woeckel A,Ismail L,Bühren A,Toth B

更新日期：2014-09-01 00:00:00

abstract：:Aim: Effective pain management during labour is important because pain affects the birth experience. Epidural analgesia is effective but often it may not be possible; however, inhaled analgesia offers another option. Use of inhaled nitrous oxide and oxygen for pain management in labour is well established in obstetric...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Dammer U,Weiss C,Raabe E,Heimrich J,Koch MC,Winkler M,Faschingbauer F,Beckmann MW,Kehl S

更新日期：2014-07-01 00:00:00

abstract：:Treatment with monoclonal antibodies (mabs) has become an established component of oncological therapy. The monoclonal antibodies available for this purpose are mainly administered intravenously in individually adapted doses according to body weight over longer treatment times. For other chronic diseases such as, for ...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Jackisch C,Müller V,Maintz C,Hell S,Ataseven B

更新日期：2014-04-01 00:00:00

abstract：:Smooth muscle neoplasms with atypical proliferative behaviour, but without clear histopathological malignancy represent a diagnostic and therapeutic challenge, as distinction from a sarcoma can be difficult and no guaranteed treatment recommendations are available due to the rarity of these changes. In the event of un...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Esch M,Teschner M,Braesen JH

更新日期：2014-03-01 00:00:00

abstract：:Suburethral tension-free vaginal tape is used for the treatment of stress urinary incontinence with a high success rate. Often patients report having stress incontinence, as well as co-existing micturition problems which are attributable to overactive bladder syndrome (OAB). The present study examines the effect of su...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Hensel G,Koštál M,Göbel J

更新日期：2014-01-01 00:00:00

abstract：:Introduction: A newly adapted clip system for intramammary marking during ultrasound-guided core needle biopsy for suspicion of breast cancer is described and evaluated here. Material and Method: Fifty patients with suspicion of breast cancer (cT2) had ultrasound-guided core needle biopsy using a newly adapted clip ma...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Schulz-Wendtland R,Dankerl P,Dilbat G,Bani M,Fasching PA,Heusinger K,Lux MP,Loehberg CR,Jud SM,Rauh C,Bayer CM,Beckmann MW,Uder M,Meier-Meitinger M,Brehm B

更新日期：2013-11-01 00:00:00

abstract：:On account of the good prognosis for patients with breast cancer, improving or maintaining the quality of life in the aftercare period is becoming more and more important. In particular, the increasing usage of aromatase inhibitors in the past few years has led to an increased incidence of vaginal atrophy with symptom...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Moegele M,Buchholz S,Seitz S,Lattrich C,Ortmann O

更新日期：2013-10-01 00:00:00

abstract：:In July 2012 a revised terminology on colposcopic examinations of the cervix uteri was adopted by IFCPC. Central aspect is a description of characteristics that should aid in the definition of the disease entity cervix uteri. The nomenclature is built up in such a way that the examiner can evaluate colposcopic criteri...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Quaas J,Reich O,Frey Tirri B,Küppers V

更新日期：2013-09-01 00:00:00

abstract：:This report shows that even extremely large nascent uterine myomas can be removed vaginally. A 25-year-old nulligravid and nulliparous patient with malaise, hypermenorrhea, and intermittent cramping pain in the lower abdomen was referred to our clinic. Gynecological examination revealed a round cauliflower-like tumor,...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Terzic M,Maricic S,Dotlic J

更新日期：2013-07-01 00:00:00

abstract：:Introduction: Bisphosphonates are well known above all for their use in the treatment of osteoporosis. They also play an important role as accompanying therapy for advanced tumour diseases with extensive spread into the skeletal system. Their adjuvant use in the treatment of breast cancer without bony metastases is cu...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Fick EM,Anzeneder T,Katalinic A,Waldmann A

更新日期：2013-05-01 00:00:00

abstract：:With the development of a National Cancer Plan published in 2012, Germany has followed the recommendations of the WHO and the EU. The first area of action listed in Germany's National Cancer Plan is improving the early detection of cancer. Both citizens and medical specialists are encouraged to take responsibility the...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Simoes E,Brucker S,Beckmann MW,Ortmann O,Albring C,Wallwiener D

更新日期：2013-03-01 00:00:00

abstract：:Aim: Nodal status remains one of the most important prognostic factors in breast cancer. The cellular and molecular reasons for the spread of tumor cells to the lymph nodes are not well understood and there are only few predictors in addition to tumor size and multifocality that give an insight into additional mechani...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Hack CC,Häberle L,Geisler K,Schulz-Wendtland R,Hartmann A,Fasching PA,Uder M,Wachter DL,Jud SM,Loehberg CR,Lux MP,Rauh C,Beckmann MW,Heusinger K

更新日期：2013-02-01 00:00:00

abstract：:The value of transvaginal ultrasound in gynaecological examinations is beyond dispute. But it is of particular forensic importance that the validity of this type of imaging with regard to the reliable detection of early-stage malignancy is properly understood. Vaginal ultrasound screening in asymptomatic patients for ...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Steiner E,Juhasz-Bösz I,Emons G,Kölbl H,Kimmig R,Mallmann P,für die AGO Uterus der DGGG .

更新日期：2012-12-01 00:00:00

abstract：:Case Report: A 38-year-old patient newly diagnosed with invasive ductal breast cancer wished to cryoconserve her unfertilised oocytes. Stimulation was started on the 26th day of her menstrual cycle with daily administration of 300 IE hMG s. c. and a GnRH antagonist (cetrorelix 0.25 mg s. c.). The patient additionally ...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Werling M,Tandler-Schneider A,Siemann A,Stief G,Kentenich H

更新日期：2012-11-01 00:00:00

abstract：:The therapy of choice for breast cancer patients requiring adjuvant chemo- or radiotherapy is increasingly guided by the principle of weighing the individual effectiveness of the therapy against the associated side effects. This has only been made possible by the discovery and validation of modern biomarkers. In the l...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Schmidt M,Fasching PA,Beckmann MW,Kölbl H

更新日期：2012-09-01 00:00:00

abstract：:Purpose: In the years 1993-1996 a number of presumably false-positive breast cancer diagnoses were made by a pathologist in Essen. A follow-up, undertaken 15 years later, investigated how many women had tumour recurrence and/or metastasis or had died from breast cancer. Material and Methods: A total of 151 (68 %) out ...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Hauth EA,Berkemeyer S,Jaeger H,Forsting M,Hoffmann B,Jöckel KH

更新日期：2012-06-01 00:00:00

abstract：:As a key area of gynaecology, urogynaecology has undergone impressive changes in the past few years. Together with the high prevalence of functional pelvic floor disorders, modern anaesthesia procedures and the introduction of new, innovative minimally invasive operation techniques have led to a dramatic increase in t...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Naumann G,Kölbl H

更新日期：2012-03-01 00:00:00

abstract：:Breast Care Centers that were accredited according to the German Cancer Society criteria were offered to participate in a standardized patient survey in 2010, which was conducted by the Institute for Medical Sociology, Health Services Research and Rehabilitation Science, Faculty of Human Science and Faculty of Medicin...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Kowalski C,Wesselmann S,Kreienberg R,Schulte H,Pfaff H

更新日期：2012-02-01 00:00:00

abstract：:Oncolytic viruses are replication competent "live" viruses. They infect tumor cells, replicate highly selective inside and thereby destroy them. Because of the enormous advances in the field of genetic engineering and biotechnology during the last decade, virotherapy is increasingly used within clinical trials and pro...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Hartkopf AD,Fehm T,Wallwiener M,Lauer U

更新日期：2012-02-01 00:00:00

abstract：:The information available about breast cancer risk factors has increased dramatically during the last 10 years. In particular, studies of low-penetrance genes and mammographic density have improved our understanding of breast cancer risk. In addition, initial steps have been taken in investigating interactions between...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Fasching PA,Ekici AB,Adamietz BR,Wachter DL,Hein A,Bayer CM,Häberle L,Loehberg CR,Jud SM,Heusinger K,Rübner M,Rauh C,Bani MR,Lux MP,Schulz-Wendtland R,Hartmann A,Beckmann MW

更新日期：2011-12-01 00:00:00

abstract：:14 of the 16 German Federal "Lands" ("Bundesländer") participated in the first assessment in perinatal medicine in reunited Germany. A total of stored data representing 563,480 single births were used to calculate percentile values for birth weight, size (length) at birth and circumference of the head from the 23rd we...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Voigt M,Schneider KT,Jährig K

更新日期：1996-10-01 00:00:00

abstract：:From 1987 to 1991 a total of 5035 pelviscopies were done at the Kiel University Hospital of Gynaecology. More than 90% of these were surgical pelviscopies, whereas less than 10% were diagnostic procedures only. Serious complications requiring laparotomy or repeat pelviscopy or laparotomy within 4 weeks after the origi...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Mecke H,Heuchmer R,Lehmann-Willenbrock E

更新日期：1996-09-01 00:00:00

abstract：:Recurrence in Four Consecutive Pregnancies in a Patient: We report on the recurrence of HELLP-syndrome in four consecutive pregnancies in a patient. The observation of recurrence of this rare disorder (0.2-0.8% of all pregnancies) in an otherwise healthy patient points to an immunological or genetic predisposition for...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Beinder E,Hirschmann A,Wildt L,Junker H

更新日期：1996-09-01 00:00:00

abstract：:The Problem of an Adequate Surgical Approach: Frequency of malignant teratomas is, according to the literature, 2%-10%. Examining 194 own cases (1983-1993) it was 1.5%. We found one squamous cell carcinoma (0.5%). Additionally we found 2 immature teratomas (1%). We point out the different biological behaviour of malig...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Kindermann G,Jung EM,Maassen V,Bise K

更新日期：1996-08-01 00:00:00

abstract：:The prognostic value of the PCNA-proliferative fraction as compared to conventional clinical and histomorphological factors (FIGO-stage, tumour type, histological grading, lymph node status, size of residual tumour) was investigated in 81 ovarian cancer patients. Categorisation of PCNA-expression into tumours with low...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Schönborn I,Minguillon C,Reles A,Bartel U,Lichtenegger W

更新日期：1996-07-01 00:00:00

abstract：UNLABELLED:Silent intrauterine infection is a frequent cause of preterm labour. Maternal C-reactive protein (CRP) and leukocyte count are important predictors of such infections. Treatment with corticosteroids is known to elevate leukocyte count and in this manner can possibly interfere with its accuracy as a predictor...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Winkler M,Heyl W,Reister F,Rath W

更新日期：1996-06-01 00:00:00

abstract：:Comparison of 1 mg Gemeprost-Vaginal Suppositories Serial Application versus Sulproston i.v.: Three different regimens for the termination of second and third trimester pregnancies by the use of prostaglandins (PG) were compared in a retrospective analysis. In group A (n = 16) terminations were attempted by continuous...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Müller T,Backe J,Rempen A

更新日期：1996-05-01 00:00:00

abstract：:To investigate the accuracy of a single high-speed core biopsy, in 159 stereotactically localised nonpalpable breast lesions a single high-speed core biopsy was performed prior to open surgery. All pathological findings of the specimen, core biopsies and open biopsies, were compared. Two biopsies were technically insu...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Goerttler-Krauspe I,Tschammler A,Forster-Sperling P

更新日期：1996-04-01 00:00:00

abstract：:A retrospective study was carried out to compare the results of in vitro fertilisation (IVF) in 20936 patients with different sperm parameters who underwent IVF in Germany between 1990 and 1993. The study was designed to evaluate prognostic factors for IVF outcome, such as sperm parameters and pre-treatment diagnosis....

journal_title：Geburtshilfe und Frauenheilkunde

authors： Tandler-Schneider A,Haeske-Seeberg H,Seeberg B,Schmiady H,Kentenich H

更新日期：1996-03-01 00:00:00

abstract：:121 patients with advanced ovarian cancer resistant to or relapsing following platinum-based chemotherapy participated in this prospective randomised multicenter study. The second-line treatment was indicated according to the relapse-free interval. 36 assessable patients were resistant to platinum-based chemotherapy o...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Kuhn W,Schmalfeldt B,Dose J,Pache L,Ulm K,Freitag K,Jänicke F,Graeff H

更新日期：1996-02-01 00:00:00

abstract：:We reported on the results of 703 breast reduction operations performed by a modified technique after McKissock/Strömbeck. Altogether we operated in the last 10 years 360 patients (15-65 years; mean 32 years) at the Johanniter Hospital in Geesthacht. Only such patients were operated on for whom a medical necessity for...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Heilenkötter U,Teuteberg V,Bahnsen J,Jatella P

更新日期：1996-01-01 00:00:00

abstract：UNLABELLED:Perineal ultrasound was used with a new measurement method that locates the urethrovesical junction. The aim of this study was to test the reproducibility of this examination. Two different investigators examined 40 patients at rest and during Valsalva's manoeuvre. Using a rectangular coordinate system, the ...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Fink D,Schär G,Köchli OR,Perucchini D,Haller U

更新日期：1995-12-01 00:00:00

abstract：:The past 30 years have seen dramatic advances concerning safety of the unborn child unsurpassed during 2400 years before, i.e. since the time of Hippocrates. Part of these advances is fetal monitoring during labor. It has recently been recognized that severe brain damage due to intrapartum fetal hypoxia is more rare t...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Saling E

更新日期：1995-11-01 00:00:00

abstract：:According to a judgement by the German Federal Court of 17 December 1991 the surgeon is legally bound to inform the patient before hand of the risk of a possible homologous blood transfusion during surgery. If the transfusion probability exceeds 5%, this obligation is really relevant, 228 patients with primary breast ...

journal_title：Geburtshilfe und Frauenheilkunde

authors： Gerber B,Arndt M,Wesselburg C,Krause A

更新日期：1995-10-01 00:00:00